Treatment of infections caused by organisms sensitive to levofloxacin, such as:
– Nosocomial pneumonia.
– Community-acquired pneumonia due to methicillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae (including multi-drug-resistant strains [MDRSP]), Haemophilus influenzae, Haemophilus parainfluenzae, Mycoplasma pneumoniae or Chlamydophila pneumoniae.
– Complicated skin and skin structure infections.
– Uncomplicated urinary tract infections due to Escherichia coli, Klebsiella pneumoniae, or Staphylococcus saprophyticus ho?c Acute pyelonephritis caused by Escherichia coli, including cases with concurrent bacteremia .
– Acute bacterial sinusitis: Because fluoroquinolones, including levofloxacin, have been associated with serious adverse reactions [see Warnings and Precautions], and for some patients with acute bacterial sinusitis is self-limiting, reserve levofloxacin for treatment of acute bacterial sinusitis in patients who have no alternative treatment options.

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